| № | City | Airport | IATA code | ICAO code |
| 1 | Bluefields | Bluefields | BEF | MNBL |
| 2 | Bonanza | Bonanza San Pedro Airport (Nicaragua) | BZA | MNBZ |
| 3 | Corn Island | Corn Island | RNI | MNCI |
| 4 | Guacalito de La Isla | Guacalito de la Isla Costa Esmeralda | ||
| 5 | Managua | Managua Augusto Cesar Sandino | MGA | MNMG |
| 6 | Ometepe Island | Ometepe La Paloma | ||
| 7 | Puerto Cabezas | Puerto Cabezas Bilwi | PUZ | MNPC |
| 8 | Rivas | Rivas Costa Esmeralda | ECI | MNCE |
| 9 | Rosita | Rosita | RFS | MNRT |
| 10 | San Carlos | San Carlos Airport (Nicaragua) | NCR | MNSC |
| 11 | Siuna | Siuna | SIU | MNSI |
| 12 | Waspam | Waspam | WSP | MNWP |