| Country | Cuba |
|---|
The airline’s main hub is José Martí International Airport.
| № | City | Country | Airport | IATA code | ICAO code |
| 1 | Baracoa | Cuba | Baracoa | BCA | MUBA |
| 2 | Bayamo | Cuba | Bayamo Carlos Manuel de Cespedes | BYM | MUBY |
| 3 | Bogota | Colombia | Bogota El Dorado International | BOG | SKBO |
| 4 | Buenos Aires, BA | Argentina | Buenos Aires Ezeiza International | EZE | SAEZ |
| 5 | Camaguey | Cuba | Camaguey International | CMW | MUCM |
| 6 | Cancun | Mexico | Cancun International | CUN | MMUN |
| 7 | Caracas | Venezuela | Caracas Simon Bolivar International | CCS | SVMI |
| 8 | Cayo Coco | Cuba | Cayo Coco | CCC | MUCC |
| 9 | Cayo Largo Del Sur | Cuba | Cayo Largo del Sur | CYO | MUCL |
| 10 | Cienfuegos | Cuba | Cienfuegos | CFG | MUCF |
| 11 | Fort De France | Martinique | Fort-de-France Martinique Aime Cesaire International | FDF | TFFF |
| 12 | Guantanamo | Cuba | Guantanamo Los Canos | GAO | MUGT |
| 13 | Havana | Cuba | Havana Jose Marti International | HAV | MUHA |
| 14 | Holguin | Cuba | Holguin Frank Pais | HOG | MUHG |
| 15 | Las Tunas | Cuba | Las Tunas | VTU | MUVT |
| 16 | Madrid, SP | Spain | Madrid Barajas | MAD | LEMD |
| 17 | Managua | Nicaragua | Managua Augusto Cesar Sandino | MGA | MNMG |
| 18 | Manzanillo | Cuba | Manzanillo Sierra Maestra | MZO | MUMZ |
| 19 | Mexico City | Mexico | Mexico City Juarez International | MEX | MMMX |
| 20 | Moa | Cuba | Moa Orestes Acosta | MOA | MUMO |
| 21 | Nassau | Bahamas | Nassau Lynden Pindling International | NAS | MYNN |
| 22 | Nueva Gerona | Cuba | Nueva Gerona Rafael Cabrera | GER | MUNG |
| 23 | Paris | France | Paris Orly | ORY | LFPO |
| 24 | Pointe A Pitre | Guadeloupe | Pointe A Pitre Le Raizet | PTP | TFFR |
| 25 | San Jose | Costa Rica | San Jose Juan Santamaria International | SJO | MROC |
| 26 | Santa Clara | Cuba | Santa Clara Abel Santamaria | SNU | MUSC |
| 27 | Santiago | Cuba | Santiago de Cuba Antonio Maceo | SCU | MUCU |
| 28 | Toronto, ON | Canada | Toronto Pearson International | YYZ | CYYZ |
| 29 | Varadero | Cuba | Varadero Juan Gualberto Gomez | VRA | MUVR |